Daisuke Urabe
Abstract
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Saxitoxin, a paralytic shellfish poison, is potent neurotoxin characterized by highly functionalized architecture including bis-guanidinium and oxygenated pyrrolidine. Recent total syntheses of saxitoxin and its analogue by Du Bois and Nagasawa groups are discussed on this mini review.
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Saxitoxin, a paralytic shellfish poison, is potent neurotoxin characterized by highly functionalized architecture including bis-guanidinium and oxygenated pyrrolidine. Recent total syntheses of saxitoxin and its analogue by Du Bois and Nagasawa groups are discussed on this mini review.
Key concepts: Saxitoxin, Neurotoxin, Chemistry, Paralytic shellfish poisoning, Toxin, Computational biology, Biology, Biochemistry