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STUDY ON THE EXCRETION OF P$sup 32$ INJECTED SUBCUTANEOUSLY. III. INFLUENCE OF X-IRRADIATION OF THE WHOLE BODY

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Abstract

After whole-body irradiation, P/sup 3//sup 2/ was injected into the subcutis of mice. In groups given 30 r and 60 r irradiation, the uptake rate of P/sup 3//sup 2/ by the tissue was relatively high immediately after irradiation, and may be due to a so-called irradiation shock. In the animals irradiated by 100 r, no such effect resulted. After that the uptake rate was gradually increased approximately in parallel with an increase of histiocytes in the connective tissue. The excretion of P/sup 3//sup 2/ showed a maximum level after 5 days in the 100 r irradiation group. This was quite similar to the uptake rate described above. The excretion of P/sup 3//sup 2/ from the subcutis directly through the blood stream appeared rather decreased compared with the control. (Absts. Japan. Med., 1: No. 7, 1960.)

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After whole-body irradiation, P/sup 3//sup 2/ was injected into the subcutis of mice. In groups given 30 r and 60 r irradiation, the uptake rate of P/sup 3//sup 2/ by the tissue was relatively high immediately after irradiation, and may be due to a so-called irradiation shock. In the animals irradiated by 100 r, no such effect resulted. After that the uptake rate was gradually increased approximately in parallel with an increase of histiocytes in the connective tissue. The excretion of P/sup 3//sup 2/ showed a maximum level after 5 days in the 100 r irradiation group. This was quite similar to the uptake rate described above. The excretion of P/sup 3//sup 2/ from the subcutis directly through the blood stream appeared rather decreased compared with the control. (Absts. Japan. Med., 1: No. 7, 1960.)

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Available abstract

After whole-body irradiation, P/sup 3//sup 2/ was injected into the subcutis of mice. In groups given 30 r and 60 r irradiation, the uptake rate of P/sup 3//sup 2/ by the tissue was relatively high immediately after irradiation, and may be due to a so-called irradiation shock. In the animals irradiated by 100 r, no such effect resulted. After that the uptake rate was gradually increased approximately in parallel with an increase of histiocytes in the connective tissue. The excretion of P/sup 3//sup 2/ showed a maximum level after 5 days in the 100 r irradiation group. This was quite similar to the uptake rate described above. The excretion of P/sup 3//sup 2/ from the subcutis directly through the blood stream appeared rather decreased compared with the control. (Absts. Japan. Med., 1: No. 7, 1960.)

Key concepts: Excretion, Irradiation, Connective tissue, Chemistry, Whole body irradiation, Radiochemistry, Medicine, Pathology

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