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EFFECT OF X-RAYS ON BONE STUDIED BY MEANS OF Ca$sup 4$$sup 5$

Miyako Umehara

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Abstract

BS>During the first 24 hours after the injection of Ca/sup 4//sup 5/, a rapid increase of calcium accumulation in the bone was observed. When the shins of mice into which Ca/sup 4//sup 5/ was injected were exposed to 3000 to 9000 r of x rays, the calcium accumulation immediately decreased in the irradiated bone. When a small dose (300 r) was applied, no perceptible change in the calcium accumulation was observed. The uptake of Ca/sup 4//sup 5/ injected was much less in the young mice than in the mature mice. About 20 days after irradiation of 2400 r the length and weight of the tibia decreased slightly but significantly as compared with the control shins. This decrease was especially pronounced in the young mice. (Abstr. Japan Med., 1: No. 2, 1960)

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BS>During the first 24 hours after the injection of Ca/sup 4//sup 5/, a rapid increase of calcium accumulation in the bone was observed. When the shins of mice into which Ca/sup 4//sup 5/ was injected were exposed to 3000 to 9000 r of x rays, the calcium accumulation immediately decreased in the irradiated bone. When a small dose (300 r) was applied, no perceptible change in the calcium accumulation was observed. The uptake of Ca/sup 4//sup 5/ injected was much less in the young mice than in the mature mice. About 20 days after irradiation of 2400 r the length and weight of the tibia decreased slightly but significantly as compared with the control shins. This decrease was especially pronounced in the young mice. (Abstr. Japan Med., 1: No. 2, 1960)

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Available abstract

BS>During the first 24 hours after the injection of Ca/sup 4//sup 5/, a rapid increase of calcium accumulation in the bone was observed. When the shins of mice into which Ca/sup 4//sup 5/ was injected were exposed to 3000 to 9000 r of x rays, the calcium accumulation immediately decreased in the irradiated bone. When a small dose (300 r) was applied, no perceptible change in the calcium accumulation was observed. The uptake of Ca/sup 4//sup 5/ injected was much less in the young mice than in the mature mice. About 20 days after irradiation of 2400 r the length and weight of the tibia decreased slightly but significantly as compared with the control shins. This decrease was especially pronounced in the young mice. (Abstr. Japan Med., 1: No. 2, 1960)

Key concepts: Calcium, Chemistry, Irradiation, Isotopes of calcium, Tibia, Radiochemistry, Endocrinology, Internal medicine

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