Clinical distribution and antibiotic resistance of 116 strains of Acinetohacter baumannii.

OBJECTIVE To analyze the drug resistance of 141 clinical strains of Acinetobacter baumannii to 15 kinds of antimicrobial agents for the rational application of antimicrobial agents.METHODS Using disk diffusion method(K-B) for drug susceptibility testing,and drug sensitivity test of 116 A.baumannii to antibiotics was analyzed retrospectively.RESULTS The A.baumannii strains mainly distributed in sputum and bronchial aspiration,followed by pus and secretions with serious drug-resistant to antibiotics.The main departments was ICU,followed by the Respiratory Department.The highest resistance rate was to gentamicin(82.76%).The lowest resistance rate of A.baumannii to the antimicrobial agents was to imipenem(6.9%),then was to meropenem(13.79%) and cefoperazone/sulbactam(23.28%).The resistance rate to other antimicrobial agents was to about or more than 50%.CONCLUSIONS The most of A.baumannii isolates are susceptible to meropenem,imipenem,and cefoperazone/sulbactam and resistant to other antimicrobial agents,therefore,we should enhance to this kind of isolates detection.