2008•Journal of the Korean Radiological SocietyRequires access
Diagnostic Value of Dynamic Perfusion MR Imaging in Benign and Malignant Musculoskeletal Lesions
Byeong Kyoo Choi, Sang Hoon Lee, Ji Hyeon, Sung Moon Kim, Myung Jin Shin, Heon Han, Sam Soo Kim, Ji Yeon Lee, Yong Hwan Jeon
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Abstract
Purpose: To assess the diagnostic value of dynamic perfusion MR imaging for differentiation between benign and malignant musculoskeletal lesions. Materials and Methods: Dynamic perfusion MR imaging was performed using a 3.0 T system in 32 female and 30 male patients (aged 10-90 years, mean age, 43 years). Following the assessment of the precontrast imaging, a dynamic study was performed. This dynamic technique allowed for 638 images to be obtained at 11 levels throughout the lesion. Twenty-eight lesions originated within bone (8 benign, 20 malignant), whereas 34 lesions were of soft tissue origin (22 benign, 12 malignant). The final diagnosis was histopathologically confirmed in all patients. To differentiate between benign and malignant lesions, we analyzed the four parameters: (maximal relative enhancement (MRE), time to peak (TTP), wash in rate (WI), steepest slope (SS) and the distribution of time intensity curve (TIC) patterns. Results: The TTP, WI, and SS values of malignant lesions were statistically significant from those of benign lesions (p