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2016•Diabetes CareRequires access

Retinal Nerve Fiber Layer Loss in Patients With Type 2 Diabetes and Diabetic Neuropathy

Hae-Young Lopilly Park, Ju‐Young Shin, Jae‐Hyung Lee, Chan Kee Park

Open publisher page 8 citations

Abstract

Retinal nerve fiber layer (RNFL) loss is commonly observed in patients with diabetes and has correlations with the stage of diabetic retinopathy (DR) (1). However, several reports have shown RNFL loss in patients with diabetes independent of DR, suggesting that the function of neuronal cells in the retina is compromised even before the appearance of overt microvascular changes (2–4). We hypothesized that RNFL loss in patients with diabetes without overt DR may represent a distinct type of diabetic neuropathy. Analyses of the status of peripheral neuropathy and cardiac autonomic neuropathy (CAN) were compared according to the location (superior or inferior) of RNFL loss in patients with type 2 diabetes without DR. We performed a retrospective review of all patients with type 2 diabetes who underwent assessment of …

About this research paper

What this paper is about

Retinal nerve fiber layer (RNFL) loss is commonly observed in patients with diabetes and has correlations with the stage of diabetic retinopathy (DR) (1). However, several reports have shown RNFL loss in patients with diabetes independent of DR, suggesting that the function of neuronal cells in the retina is compromised even before the appearance of overt microvascular changes (2–4). We hypothesized that RNFL loss in patients with diabetes without overt DR may represent a distinct type of diabetic neuropathy. Analyses of the status of peripheral neuropathy and cardiac autonomic neuropathy (CAN) were compared according to the location (superior or inferior) of RNFL loss in patients with type 2 diabetes without DR. We performed a retrospective review of all patients with type 2 diabetes who underwent assessment of …

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OpenAlex reports 8 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Retinal nerve fiber layer (RNFL) loss is commonly observed in patients with diabetes and has correlations with the stage of diabetic retinopathy (DR) (1). However, several reports have shown RNFL loss in patients with diabetes independent of DR, suggesting that the function of neuronal cells in the retina is compromised even before the appearance of overt microvascular changes (2–4). We hypothesized that RNFL loss in patients with diabetes without overt DR may represent a distinct type of diabetic neuropathy. Analyses of the status of peripheral neuropathy and cardiac autonomic neuropathy (CAN) were compared according to the location (superior or inferior) of RNFL loss in patients with type 2 diabetes without DR. We performed a retrospective review of all patients with type 2 diabetes who underwent assessment of …

Key concepts: Medicine, Diabetes mellitus, Type 2 diabetes, Nerve fiber layer, Diabetic retinopathy, Retinal, Ophthalmology, Peripheral neuropathy

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Retinal Nerve Fiber Layer Loss in Patients With Type 2 Diabetes and Diabetic Neuropathy — Research Paper | ScholarLens