Photostabilization of Azadirachtin A
M Alimuddin Khan, Dinesh B. Saxena, Najam Akhtar Shakil, Ashok Kumar Gupta
Abstract
M Alimuddin Khan, Dinesh B. Saxena, Najam Akhtar Shakil, Ashok Kumar Gupta
Abstract
Studies have been conducted to stabilize azadirachtin - A with neem oil, neem meliacins and some known stabilizers. Neem oil and butylated hydroxy anisole (BHA) gave maximum stability to aza-A. When methanolic solution of aza-A and neem oil (1:1), and aza-A and BHA (9:1) were exposed to sun light, T1/2. was found to be 5.68 and 3.67 d respectively while that of aza-A alone was 1.76 d only. Further, the antifeedant activity of aza-A against tobacco armyworm, Spodoptera litura Fab was considerably enhanced following incorporation of BHA and neem oil. Fifty two and 27% antifeedancy were observed with aza-A mixed with neem oil and BHA respectively as compared to 10% antifeedancy observed with aza-A alone. The apparent enhancement in antifeedant activity was attributed to the possible stabilizing effect of neem oil and BHA.
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Studies have been conducted to stabilize azadirachtin - A with neem oil, neem meliacins and some known stabilizers. Neem oil and butylated hydroxy anisole (BHA) gave maximum stability to aza-A. When methanolic solution of aza-A and neem oil (1:1), and aza-A and BHA (9:1) were exposed to sun light, T1/2. was found to be 5.68 and 3.67 d respectively while that of aza-A alone was 1.76 d only. Further, the antifeedant activity of aza-A against tobacco armyworm, Spodoptera litura Fab was considerably enhanced following incorporation of BHA and neem oil. Fifty two and 27% antifeedancy were observed with aza-A mixed with neem oil and BHA respectively as compared to 10% antifeedancy observed with aza-A alone. The apparent enhancement in antifeedant activity was attributed to the possible stabilizing effect of neem oil and BHA.
Key concepts: Neem oil, Azadirachtin, Spodoptera litura, Chemistry, Neem cake, Toxicology, Food science, Organic chemistry