2002•Iranian Journal of PediatricsRequires access

Antibiotic resistance of germs isolated from urinary tract infections

Q Khotayi, S Mameshi, R Najjar Saliqeh

Open publisher page 9 citations

Abstract

The pathogens in urine specimens of 90 pediatric patients with urinary tract infection were isolated and their resistance to antibiotics in antibiogram determined. The most common pathogen was found to be E coli (In 77.7% of specimens). The most effective antibiotics were i.v amikacin (Sensitivity in 91.5% of cases) and oral nalidixic acid (In 76.9% of specimens) whereas ampicillin was the most ineffective antibiotic (Resistance in 87.5% of specimens). Therapy in urinary tract infections is commonly started with ampicillin and gentamicin. Considering that 39.5% of pathogens isolated in our study were resistant to both of thee antibiotics, preparation of antibiograms to find the most effective antibacterial in all cases of urinary tract infection is highly recommended.

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What this paper is about

The pathogens in urine specimens of 90 pediatric patients with urinary tract infection were isolated and their resistance to antibiotics in antibiogram determined. The most common pathogen was found to be E coli (In 77.7% of specimens). The most effective antibiotics were i.v amikacin (Sensitivity in 91.5% of cases) and oral nalidixic acid (In 76.9% of specimens) whereas ampicillin was the most ineffective antibiotic (Resistance in 87.5% of specimens). Therapy in urinary tract infections is commonly started with ampicillin and gentamicin. Considering that 39.5% of pathogens isolated in our study were resistant to both of thee antibiotics, preparation of antibiograms to find the most effective antibacterial in all cases of urinary tract infection is highly recommended.

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Available abstract

The pathogens in urine specimens of 90 pediatric patients with urinary tract infection were isolated and their resistance to antibiotics in antibiogram determined. The most common pathogen was found to be E coli (In 77.7% of specimens). The most effective antibiotics were i.v amikacin (Sensitivity in 91.5% of cases) and oral nalidixic acid (In 76.9% of specimens) whereas ampicillin was the most ineffective antibiotic (Resistance in 87.5% of specimens). Therapy in urinary tract infections is commonly started with ampicillin and gentamicin. Considering that 39.5% of pathogens isolated in our study were resistant to both of thee antibiotics, preparation of antibiograms to find the most effective antibacterial in all cases of urinary tract infection is highly recommended.

Key concepts: Ampicillin, Amikacin, Nalidixic acid, Gentamicin, Medicine, Antibiotics, Urinary system, Microbiology

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