2010•Zhongguo yiyuan ganranxue zazhiRequires access

Ten types of mobile genetic elements detected from multidrug-resistant Escherichia coli.

Wang WeiHua, Jie Chen, Li Wang, LüWanFei, Yuanyuan Zhang, Mao Xiongying, Hui Chen

Abstract

OBJECTIVE To investigate the prevalence of mobile genetic elements in isolates of multidrug-resistant Escherichia coli.METHODS A total of 20 strains of MDR-ECO isolated from Oct 2009 to Mar 2010 were collected,10 types of mobile genetic elements were detected by polymerase chain reaction(PCR),then the results were analyzed and partly sequenced.RESULTS A total of 6 types of mobile genetic elements were found existing among 20 isolates,namely traA,trbC,tnp513,ISEcp1,IS26 and intⅠ1.CONCLUSION Mobile genetic elements,such as conjugated plasmid,transposable element,and integron group Ⅰ,may play an important role in the multidrug-resistance of E.coli.

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Key concepts: Mobile genetic elements, Integron, Multiple drug resistance, Escherichia coli, Biology, Transposable element, Plasmid, Microbiology