ChemInform Abstract: CaCl2, Bisoxazoline, and Malonate: A Protocol for an Asymmetric Michael Reaction.
Kristin Lippur, Sandra Kaabel, Ivar Jaerving, Kari Rissanen, Tõnis Kanger
Abstract
Kristin Lippur, Sandra Kaabel, Ivar Jaerving, Kari Rissanen, Tõnis Kanger
Abstract
Abstract It is demonstrated, that a catalytic system composed of CaCl2 and a pyridine‐bisoxazoline ligand efficiently promotes the asymmetric Michael addition of α,β‐unsaturated ketones with dimethyl malonate.
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Abstract It is demonstrated, that a catalytic system composed of CaCl2 and a pyridine‐bisoxazoline ligand efficiently promotes the asymmetric Michael addition of α,β‐unsaturated ketones with dimethyl malonate.
Key concepts: Chemistry, Dimethyl malonate, Malonate, Michael reaction, Pyridine, Diethyl malonate, Ligand (biochemistry), Catalysis