Michael Addition Catalyzed by Potassium Hydroxide Under Ultrasound
Ji‐Tai Li, Yong Cui, Guofeng Chen, Zhao‐Li Cheng, Tong‐Shuang Li
Abstract
Ji‐Tai Li, Yong Cui, Guofeng Chen, Zhao‐Li Cheng, Tong‐Shuang Li
Abstract
Michael addition of chalcone with active methylene compound such as diethyl malonate, nitromethane and ethyl acetoacetate catalyzed by potassium hydroxide in anhydrous ethanol results Michael adducts in 75–98% yield under ultrasound irradiation in 25–90 min.
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Michael addition of chalcone with active methylene compound such as diethyl malonate, nitromethane and ethyl acetoacetate catalyzed by potassium hydroxide in anhydrous ethanol results Michael adducts in 75–98% yield under ultrasound irradiation in 25–90 min.
Key concepts: Chemistry, Michael reaction, Nitromethane, Potassium hydroxide, Diethyl malonate, Dimethyl malonate, Chalcone, Catalysis