2001•Indian Journal of Pharmaceutical SciencesRequires access

Antiinflammatory Activity Of Various Extracts Of Pergularia Extensa N.E.BR (Asclepiadaceae)

Vijaykumar I. Hukkeri, Madhukar B. Patil, Sunil Satyappa Jalalpure, Ashraf F. Ali

Abstract

Crude ethanol extract of Pergularia extensa leaves was successively fractionated with petroleum ether, solvent ether, ethyl acetate, butanol and butanone. The ethanolic extract and various fractions were investigated for antiinflammatory activity in rats at a dose of 100 mg/kg intraperitoneally. Ethanol extract and its butanol fraction exhibited significant antiinflammatory activity when compared with respective controls and were comparable with that of standard drug aspirin.

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Key concepts: Petroleum ether, Chemistry, Ethyl acetate, Butanone, Butanol, Ethanol, Ether, Solvent