2000•Indian Journal of Pharmaceutical SciencesRequires access

Antiinflammatory And Analgesic Activity Of Various Extracts Of Leucas Aspera Spreng (Labiatae)

Anand R. Saundane, K. M Hidayat Ulla, Nayak Devappa Satyanarayan

Abstract

Four different crude extracts petroleum ether, chloroform, ethanol and water of Leucas aspera Spreng were investigated for antiinflammatory and analgesic activities in albino rats and mice, respectively at a dose of 400 mg/kg body weight, orally. Ethanol and distilled water extracts exhibited significant antiinflammatory activity, whereas significant analgesic effect was shown by petroleum ether and ethanol extract when compared with respective controls and were comparable with those of standard drugs, diclofenac sodium and analgin.

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Key concepts: Petroleum ether, Analgesic, Diclofenac Sodium, Chemistry, Chloroform, Traditional medicine, Ethanol, Distilled water