2016•Journal of Drug Design and Medicinal ChemistryOpen access

Antimicrobial Potential of Glycyrrhiza glabra

Asad Abbas, Muhammad Sulaiman Zubair, Nasır Rasool, Komal Rızwan

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Abstract

This study was carried out to evaluate the antimicrobial activity of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of Glycyrrhiza glabra root. The antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (MIC) against a panel of microorganisms (four bacterial strains, i.e P. multocida, E. coli, B. subtilis and S. aureus and three fungal strains, i.e. A. flavus, A. niger and R. solani). The results indicated that plant extract and fractions mildly potent as antimicrobial agent.

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What this paper is about

This study was carried out to evaluate the antimicrobial activity of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of Glycyrrhiza glabra root. The antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (MIC) against a panel of microorganisms (four bacterial strains, i.e P. multocida, E. coli, B. subtilis and S. aureus and three fungal strains, i.e. A. flavus, A. niger and R. solani). The results indicated that plant extract and fractions mildly potent as antimicrobial agent.

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Available abstract

This study was carried out to evaluate the antimicrobial activity of methanolic extract and different fractions (n-butanol, ethyl acetate, chloroform and n-hexane) of Glycyrrhiza glabra root. The antimicrobial activity was determined by the disc diffusion method and minimum inhibitory concentration (MIC) against a panel of microorganisms (four bacterial strains, i.e P. multocida, E. coli, B. subtilis and S. aureus and three fungal strains, i.e. A. flavus, A. niger and R. solani). The results indicated that plant extract and fractions mildly potent as antimicrobial agent.

Key concepts: Antimicrobial, Glycyrrhiza, Minimum inhibitory concentration, Ethyl acetate, Traditional medicine, Staphylococcus aureus, Chemistry, Microbiology

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