The effect of RADIX OPLOPANACIS ELATI on Immune Function in Mice with Low Immunity

[Objective] To discuss the effects of RADIX OPLOPANACIS ELATI on immune function in immunosuppressive mice.[Method] Immunosuppressive mice model was established by intraperitoneal injection with cyclophosphamide followed by daily intragastric administration of extracts of RADIX OPLOPANACIS ELATI.After the treatment,the mice were examined for observing the effects of extracts on the immune organ index,the carbon particle clearance of mononuclear phagocyte and the delayed type hypersensitivity induced by 2,4-dinitrochlorobenzene in experimental animals.[Results] Results showed that the immune organ index,the phagocytic function of mononuclear phagocyte and the delayed type hypersensitivity in the three dose groups mice which were respectively fed with extracts of RADIX OPLOPANACIS ELATI at the daily dose of 5.2,2.6 and 1.3 g/kg were significant increased when compared to the CY model group.[Conclusion] RADIX OPLOPANACIS ELATI extracts could enhance the immune function of immunosuppressive mice induced by cyclophosphamide.