Evaluation of platelet count and indices in pulmonary tuberculosis and pneumonia

Recent studies show that platelets (Plt.) have important roles in the immune system. It is known that MPV (mean platelet volume) and PDW (platelet distribution width) increase during platelet activation. Some research indicates their roles in coronary artery disease, thromboembolic disease and endotoxemia. The aim of our study, changes in platelet count and indices are investigated in pulmonary tuberculosis and pneumonia. Platelet count and indices were evaluated in 98 patients with active tuberculosis (mean age 38.78±15.42) and 35 patients with pneumonia (mean age 40.46±17.34) and 20 healthy control (mean age 36.20±11.62). Radiological extents of the diseases were assessed. In the active tuberculosis group values were significantly higher (Plt: 381683±125046; MPV: 8.57±1.39; PDW: 14.67±2.10; PCT (plateletcrit): 0.31±0.09) than pneumonia group (Plt: 283457±76101; MPV: 8.74±0.55; PDW: 13.74±1.34; PCT: 0.25±0.04) and healthy control group (Plt: 266150±55084; MPV: 8.57±0.42; PDW: 12.84±0.86; PCT: 0.24±0.03). In the pneumonia group values were significantly lower than active tuberculosis group; but only PDW values were significantly higher than healthy control group (p