Bacterial distribution in inpatients with biliary duct infection and antibiotics sensitivity.

OBJECTIVE To observe the changes bacterial distribution in bile duct infection and the antibiotics sensitivity.METHODS The data of bile bacterial culture were studied in 1430 patients and the medicine antibiotics sensitivity was statistically analyzed.RESULTS From them 584 positive cultures from the bile were found(40.84%).Totally 469 strains of pathogens were found and they consisted of 37 kinds of bacteria and five kinds of fungi.The first four were Escherichia coli,Klebsiella pneumoniae,Enterococcus faecalis and Enterobacter cloacae,which constituted 80.00% of the biliary bacteria.They were highly sensitive to imipenem(82.14-100.00%),meropenem(57.14-100.00%),piperacilin/tazobatam(54.55-100.00%),amoxicillin/clavulanic acid(9.09-88.89%),netilmicin(21.43-100.00%),amikacin(45.45-100.00%),cefoxitin(6.89-83.33%),ceftazidime(29.63-59.26%),and cefepie(35.38-82.76%),while less sensitive to the first generation cephalosporins(18.46-35.00%),amoxicillin(0-11.67%),and ciprofloxacin(18.46-100.00%).CONCLUSION The main microbial are consist of Gram-negative bacilli.E.coli,K.pneumoniae,E.faecalis and E.cloacae.Piperacillin/tazobatam,netilmicin,amikacin,cefoxitin,ceftazidime,and cefepime are the first choice.