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2010•Pakistan Journal of PhysiologyOpen access

SHORT REVIEW OF PATHOPHYSIOLOGY OF CATECHOL ESTROGEN

Rajnee, Sunita Choudhary, Bijendra Kumar Binawara

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Abstract

In women of reproductive age, the primary source of circulating estrogens is the ovaries.  There are three forms of estrogen circulating in our bloodstream: estradiol, estrone and estriol. The normal ratio of these three types of estrogens ideally should be 10–20%, 10–20%, and 60–80% respectively. The estrogen that accounts for most of the tissue stimulation is called estradiol.  Estrone is a little bit less potent with estriol being the weakest. Brain converts estrone and estradiol to 2- and 4-hydroxylated derivatives known as catechol estrogens

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In women of reproductive age, the primary source of circulating estrogens is the ovaries.  There are three forms of estrogen circulating in our bloodstream: estradiol, estrone and estriol. The normal ratio of these three types of estrogens ideally should be 10–20%, 10–20%, and 60–80% respectively. The estrogen that accounts for most of the tissue stimulation is called estradiol.  Estrone is a little bit less potent with estriol being the weakest. Brain converts estrone and estradiol to 2- and 4-hydroxylated derivatives known as catechol estrogens

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Available abstract

In women of reproductive age, the primary source of circulating estrogens is the ovaries.  There are three forms of estrogen circulating in our bloodstream: estradiol, estrone and estriol. The normal ratio of these three types of estrogens ideally should be 10–20%, 10–20%, and 60–80% respectively. The estrogen that accounts for most of the tissue stimulation is called estradiol.  Estrone is a little bit less potent with estriol being the weakest. Brain converts estrone and estradiol to 2- and 4-hydroxylated derivatives known as catechol estrogens

Key concepts: Estrone, Estriol, Estrogen, Catechol, Endocrinology, Internal medicine, Chemistry, Medicine

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