Phytochemical Screening and In Vitro Antioxidant Activity of Saccharum Spontaneum Linn.
M Sathya, R Kokilavani
Abstract
M Sathya, R Kokilavani
Abstract
Under most pathological conditions there is generation of reactive oxygen species and other free radicals. An increase in the antioxidant reserves of the organism can reduce oxidative stress and some of the plant-derived agents may help to reduce it. The aim of this study was to evaluate in vitro antioxidant activity inhibition of DPPH, FRAP and ABTs radicals scavenging activity. Results indicate that ethanolic root extract of Saccharum spontaneum have marked high content of secondary metabolites among all the solvents. At (100-500µg/ml) concentration the S.spontaneum of 500µg/ml concentration exhibited high DPPH radical scavenging capacity using ascorbic acid as positive control. S.spontaneum at the same concentration showed the dose dependent inhibition of FRAP, and ABTs radical scavenging activity. Collectively, our results indicate that the ethanolic root extract of S.spontaneum has the potential to scavenge free radicals and act as a good antioxidant for treating various diseases.
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Under most pathological conditions there is generation of reactive oxygen species and other free radicals. An increase in the antioxidant reserves of the organism can reduce oxidative stress and some of the plant-derived agents may help to reduce it. The aim of this study was to evaluate in vitro antioxidant activity inhibition of DPPH, FRAP and ABTs radicals scavenging activity. Results indicate that ethanolic root extract of Saccharum spontaneum have marked high content of secondary metabolites among all the solvents. At (100-500µg/ml) concentration the S.spontaneum of 500µg/ml concentration exhibited high DPPH radical scavenging capacity using ascorbic acid as positive control. S.spontaneum at the same concentration showed the dose dependent inhibition of FRAP, and ABTs radical scavenging activity. Collectively, our results indicate that the ethanolic root extract of S.spontaneum has the potential to scavenge free radicals and act as a good antioxidant for treating various diseases.
Key concepts: DPPH, Antioxidant, Ascorbic acid, ABTS, Chemistry, Phytochemical, Radical, Scavenging