Histological Study of Liver Regeneration Following Partial Hepatectomy and Total Splenectomy
Kalbaza Ahmed Yacine, Amara Karim, Hemida Houari, Benchohra Mokhtar, Melizi Mohamed
Abstract
Kalbaza Ahmed Yacine, Amara Karim, Hemida Houari, Benchohra Mokhtar, Melizi Mohamed
Abstract
2 Abstract: Small for size syndrome is a major problem in hepatic surgery. The aim of this study is to investigate the effect of total splenectomy on liver regeneration following partial hepatectomy in rabbits. Animals were divided into two groups, 6 each: Hx: hepatic resection and Hx+Sp: hepatic resection and total splenectomy. Three days after skin closure, animals in the two groups were sacrificed and the remnant liver tissue was harvested to perform a histopathological examination. Animals in the Hx+Sp group have shown a pronounced liver regeneration signs compared to those of the Hx group.
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2 Abstract: Small for size syndrome is a major problem in hepatic surgery. The aim of this study is to investigate the effect of total splenectomy on liver regeneration following partial hepatectomy in rabbits. Animals were divided into two groups, 6 each: Hx: hepatic resection and Hx+Sp: hepatic resection and total splenectomy. Three days after skin closure, animals in the two groups were sacrificed and the remnant liver tissue was harvested to perform a histopathological examination. Animals in the Hx+Sp group have shown a pronounced liver regeneration signs compared to those of the Hx group.
Key concepts: Splenectomy, Hepatectomy, Liver regeneration, Medicine, Regeneration (biology), Resection, Histopathological examination, Gastroenterology