The Impact of Three-Dimensional Ultrasound of Endometrial Thickness and Volume on ICSI Outcome

Objectives: One of the most effective elements in the success of Intra Cytoplasmic Sperm Injection (ICSI) is favorable endometer. Our study was designed to find the correlation of three-dimensionally measured endometrial volume and thickness and pregnancy outcome in the women undergone ICSI. Methods and materials: This cross-sectional study was conducted by reviewing 62 patients' obstetric records undergone ICSI in age <37 yr. The endometrial thickness and volume were assessed by 3D transvaginal ultrasound at the day of Human chorionic Gonadotropin(HCG) injection. Correlation between the endometrial thickness and volume with outcome of pregnancy were evaluated and the data was analyzed. Results: The overall pregnancy rate was 26%. Mean of the endometrial thickness and volume at the day of HCG administration in the women who conceived were 11.31±2.49mm, 6.62±4.23ml respectively. Multivariate logistic regression analysis was shown that there were no significantly associations between endometrial thickness and volume with the pregnancy outcome. Conclusion: The results of the present study reveal that at least 11mm endometrial thickness and 5ml endometrial volume require achieving conception at ICSI cycles.