2010•International Journal of Research in Ayurveda and PharmacyRequires access

In-vitro anti-oxidant activity of methanolic extract of Baliospermum montanum.

B. Baburao, Jagannadha Rao Peela, Apoorva Reddy, K. Narasimha, B. Raja Narender

Abstract

The methanolic extracts of root of Baliospermum montanum were screened for antioxidant activity against DPPH, hydrogen peroxide and Nitric oxide free radicals. The methanolic extract of Baliospermum montan um (MEBM) has scavenged the DPPH, Nitric oxide and Hydrogen peroxide radicals in dose dependent manner. The experimental results were compared with the standard antioxidant ascorbic acid. The methanolic extract exhibited concentration dependant DPPH, Nitri c oxide and Hydrogen peroxide radical scavenging activity with IC 50 values of 226, 272.8 and 2 4 6.84 µg/ml respectively. The in - vitro studies reveal that the methanolic extracts of Baliospermum montanum possesses a significant antioxidant activity.

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Key concepts: Hydrogen peroxide, Chemistry, DPPH, Antioxidant, Nitric oxide, Radical, Ascorbic acid, In vitro