ScholarLens Back to search
2003•Unpublished venueRequires access

Diphenylprotoporphyrin IX by an Aerobic Reaction of Phenylhydrazine with Oxyhemoglobins

Akira Nakanishi, Keiko Kinuta, Tadashi Abe, Kenta Araki, Yumi Yoshida, Shuang A. Liang, Shun‐Ai Li, Kohji Takei, Masahiro Kinuta

Open publisher page 0 citations

Abstract

Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythrocytes, causing the formation of intracellular precipitates known as Heinz bodies, severe hemolytic anemia, and reticulocytosis. To elucidate the molecular mechanism of the destabilization, we allowed human oxyhemoglobins to react aerobically with phenylhydrazine. After

About this research paper

What this paper is about

Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythrocytes, causing the formation of intracellular precipitates known as Heinz bodies, severe hemolytic anemia, and reticulocytosis. To elucidate the molecular mechanism of the destabilization, we allowed human oxyhemoglobins to react aerobically with phenylhydrazine. After

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Administration of phenylhydrazine to rabbits resulted in the denaturation of hemoglobins in erythrocytes, causing the formation of intracellular precipitates known as Heinz bodies, severe hemolytic anemia, and reticulocytosis. To elucidate the molecular mechanism of the destabilization, we allowed human oxyhemoglobins to react aerobically with phenylhydrazine. After

Key concepts: Phenylhydrazine, Reticulocytosis, Chemistry, Biochemistry, Anemia, Medicinal chemistry, Medicine, Internal medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Diphenylprotoporphyrin IX by an Aerobic Reaction of Phenylhydrazine with Oxyhemoglobins — Research Paper | ScholarLens