Phytochemical and Pharmacological Studies of Ficus Auriculata Lour

Eight known compounds, including: betulinic acid, l upeol, stigmasterol, bergapten, scopoletin, �-sitosterol-3-O-�-D-glucopyranoside, myricetin, and quercetin-3-O-�-Dglucopyranoside were isolated from the petroleum et her, chloroform and ethyl acetate fractions of alcoholic extracts of the leaves and f ruits of Ficus auriculata Lour. The structures of these compounds were elucidated on th e basis of various spectroscopic methods. This is the first report on compounds sepa ration from Ficus auriculata Lour. (Moraceae ). Both the extracts were effective against gram +v e bacteria (Staphylococcus aureus , Bacillus aureus and Bacillus subtilis ) and gram ‐ve bacteria (Esherichia coli and Pseudomonas aeruginosa ) by agar well diffusion method. Meanwhile, the alcoholic extract of leaves at dose of 500mg/kg exhibited antiinflammatory effect using carrageenin-induced rat h ind paw oedema model. Concerning the antioxidant effect the results revea led that increasing the concentrations of the extracts increased the antiox idant effect in a dose dependant manner and the fruits extract has more antioxidant activity than the leaves. Also, the extracts showed slight hepatopratective and antidia betic activities.