The effects of Diethyl ether and Aqueous Garcinia kola seeds extracts on some bacterial isolates.

The antibacterial activity of Garcinia Kola seeds Diethyl ether and Aqueous extracts were tested against selected clinical bacterial isolates; Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa at 50, 100, 150mg/ml. Agar well diffusion method was employed to determine the Minimum Inhibitory Concentration (mm) of the extracts against test isolates. The results showed that Diethyl ether exhibit more significant activity at P<0.01 and Aqueous extracts at P<0.05, at the different treatment regimes.Similarly, the concentration of 150mg/ml produced the highest zone of inhibition (mm), while, 50mg/ml gave the least against the test isolates.Also, phytochemical compounds (Flavonoids,tannin,Saponins,Sterols, and terpenes) possibly responsible for the antibacterial activity in the plant extracts were determined. Implication of results is that Diethyl ether and Aqueous Garcinia kola seed extracts posses strong antibacterial and potentially chemotherapeutic activity and it can be useful in the treatment of bacterial infections in humans. (Ghamba, P. E. Agbo, E. B. Umar, A. F. and Bukbuk, D. N. The effects of Diethyl ether and Aqueous Garcinia kola seeds extracts on some bacterial isolates. Academia Arena, 2011;3(2):87-94) (ISSN 1553-992X). http://www.sciencepub.net .