ANALGESIC, ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITY OF PISTIASTRATIOTES L

This study was intended to evaluate the analgesic, anti-inflammatory and antipyretic activity of Pistia stratiotes , Linn. in experimental standard models i.e. albino rats following oral administration of petroleum ether and ethanolic extract. The results showed that the ethanolic extract significantly reduce the edema induced by carrageenan within 1 to 3 hrs. post dosing and Cotton-pellet induced granuloma models than the petroleum ether extract at all the dose levels used. On the analgesic property tail immersion and acetic acid induce writhing models, ethanolic extract significantly reduce the painful stimulus than petroleum ether extract. This confirms central and peripheral effects of the drugs. It also possess antipyretic activity, ethanolic extract significantly reduces fever at higher doses within 3