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FREE RADICAL SCAVENGING ACTIVITY OF METHANOLIC ROOT EXTRACT OF THE PLANT CROTOLARIA BURHIA.LINN

Gaurav Alang, Rupinder Kaur, Amrinder Singh, Pankaj Budhlakoti, Anuj Singh

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Abstract

Summary The present study was undertaken to evaluate the free radical scavenging potential of the roots of Crotolaria burhia by using different antioxidant models of screening. The methanolic extract at 1280µg/ml showed significant scavenging of the radical cation; DPPH (1, 1-diphenyl-2-picryl hydrazyl), superoxide anion (O2 .- ) and lipid peroxidation potential. The percentage scavenging effect was maximum in case of superoxide anion followed by DPPH and lipid peroxidation. In conclusion, C.burhia posses antioxidant activity which was found to be concentration dependent (increases with increase in the concentration of the extract) and thereby justifies the therapeutic value of the plant in the present era.

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What this paper is about

Summary The present study was undertaken to evaluate the free radical scavenging potential of the roots of Crotolaria burhia by using different antioxidant models of screening. The methanolic extract at 1280µg/ml showed significant scavenging of the radical cation; DPPH (1, 1-diphenyl-2-picryl hydrazyl), superoxide anion (O2 .- ) and lipid peroxidation potential. The percentage scavenging effect was maximum in case of superoxide anion followed by DPPH and lipid peroxidation. In conclusion, C.burhia posses antioxidant activity which was found to be concentration dependent (increases with increase in the concentration of the extract) and thereby justifies the therapeutic value of the plant in the present era.

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Available abstract

Summary The present study was undertaken to evaluate the free radical scavenging potential of the roots of Crotolaria burhia by using different antioxidant models of screening. The methanolic extract at 1280µg/ml showed significant scavenging of the radical cation; DPPH (1, 1-diphenyl-2-picryl hydrazyl), superoxide anion (O2 .- ) and lipid peroxidation potential. The percentage scavenging effect was maximum in case of superoxide anion followed by DPPH and lipid peroxidation. In conclusion, C.burhia posses antioxidant activity which was found to be concentration dependent (increases with increase in the concentration of the extract) and thereby justifies the therapeutic value of the plant in the present era.

Key concepts: Scavenging, DPPH, Chemistry, Antioxidant, Superoxide, Lipid peroxidation, Superoxide radical, Traditional medicine

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FREE RADICAL SCAVENGING ACTIVITY OF METHANOLIC ROOT EXTRACT OF THE PLANT CROTOLARIA BURHIA.LINN — Research Paper | ScholarLens