The elusive aldol reaction of enolates with aldolates—a highly stereoselective process using three different carbonyl components
Michael Schmittel, Andreas Haeuseler, Tom Nilges, Arno Pfitzner
Abstract
Michael Schmittel, Andreas Haeuseler, Tom Nilges, Arno Pfitzner
Abstract
Three different carbonyl components are assembled to tetrahydropyran-2,4-diols by two successive diastereoselective aldol reactions.
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Three different carbonyl components are assembled to tetrahydropyran-2,4-diols by two successive diastereoselective aldol reactions.
Key concepts: Aldol reaction, Tetrahydropyran, Stereoselectivity, Chemistry, Organic chemistry, Combinatorial chemistry, Catalysis, Ring (chemistry)