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The prognosis of HIV-infected patients with diffuse large B-cell lymphoma treated with chemotherapy and highly active antiretroviral therapy is similar to that of HIV-negative patients receiving chemotherapy.

José‐Tomás Navarro, Natàlia Lloveras, Josep‐María Ribera, Albert Oriol, José Luís Mate, Evarist Feliú

Abstract

In the era of highly active antiretroviral treatment (HAART), the prognosis of AIDS-related lymphomas might be similar to that of aggressive B-cell lymphomas in human immunodeficiency (HIV)-negative patients. In this study we found that HIV-infected patients with diffuse large B-cell lymphoma treated with cyclophosphamide, hydroxydoxorubicin, vincristine and prednisone (CHOP) and HAART showed a similar response rate to chemotherapy, disease-free survival and overall survival as those of HIV-negative patients receiving CHOP.

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Available abstract

Key concepts: Vincristine, CHOP, Chemotherapy, Medicine, Lymphoma, Cyclophosphamide, Prednisone, Internal medicine