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2013•Journal of paramedical sciences.Requires access

Synthesis and investigation of antioxidant activities of 2-benzylidene-3-coumaranones

Hadi Adibi, Alireza Foroumadi, Reza Khodarahmi‬, Karim Najafi, Mostafa Rezaei

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Abstract

A number of 6-hydroxy-2-benzylidene-3-coumaranones were synthesized from condensation of 6hydroxy-3-coumaranone with appropriate aldehydes and were evaluated for their antioxidant activities. The antioxidant activity was assessed using two methods, including, 1,1-biphenyl-2-picrylhydrazyl (DPPH) radical scavenging, and reducing power assays. Some of the benzylidene coumaranones showed antioxidant activity more than Trolox as reference antioxidant.

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What this paper is about

A number of 6-hydroxy-2-benzylidene-3-coumaranones were synthesized from condensation of 6hydroxy-3-coumaranone with appropriate aldehydes and were evaluated for their antioxidant activities. The antioxidant activity was assessed using two methods, including, 1,1-biphenyl-2-picrylhydrazyl (DPPH) radical scavenging, and reducing power assays. Some of the benzylidene coumaranones showed antioxidant activity more than Trolox as reference antioxidant.

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Available abstract

A number of 6-hydroxy-2-benzylidene-3-coumaranones were synthesized from condensation of 6hydroxy-3-coumaranone with appropriate aldehydes and were evaluated for their antioxidant activities. The antioxidant activity was assessed using two methods, including, 1,1-biphenyl-2-picrylhydrazyl (DPPH) radical scavenging, and reducing power assays. Some of the benzylidene coumaranones showed antioxidant activity more than Trolox as reference antioxidant.

Key concepts: Trolox, Antioxidant, DPPH, Chemistry, Biphenyl, Organic chemistry, Nuclear chemistry

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