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Antibacterial activity of Asperugo procumbens L. against some human pathogenic bacteria

Mohammad Ahanjan, Devihalli Chikkaiah Mohana, K. A. Raveesha

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Abstract

Petroleum ether, chloroform (CHCl3), ethanol (EtOH), methanol (MeOH) and aqueous (H2O) extracts of leaves of Asperugo procumbens L. were evaluated for antibacterial activity against five human pathogenic bacterial strains with the agar-well diffusion method. The methanol extract was highly active against all the test bacteria, followed by the ethanol and aqueous extracts. The chloroform and petroleum ether extracts did not show any antibacterial activity. The minimum inhibitory concentration (MIC) of the methanol extract ranged between 1.56 and 12.5 mg/ml. The results of this study provide support for the use of A. procumbens L. in Iran for traditional medicines.

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Petroleum ether, chloroform (CHCl3), ethanol (EtOH), methanol (MeOH) and aqueous (H2O) extracts of leaves of Asperugo procumbens L. were evaluated for antibacterial activity against five human pathogenic bacterial strains with the agar-well diffusion method. The methanol extract was highly active against all the test bacteria, followed by the ethanol and aqueous extracts. The chloroform and petroleum ether extracts did not show any antibacterial activity. The minimum inhibitory concentration (MIC) of the methanol extract ranged between 1.56 and 12.5 mg/ml. The results of this study provide support for the use of A. procumbens L. in Iran for traditional medicines.

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Available abstract

Petroleum ether, chloroform (CHCl3), ethanol (EtOH), methanol (MeOH) and aqueous (H2O) extracts of leaves of Asperugo procumbens L. were evaluated for antibacterial activity against five human pathogenic bacterial strains with the agar-well diffusion method. The methanol extract was highly active against all the test bacteria, followed by the ethanol and aqueous extracts. The chloroform and petroleum ether extracts did not show any antibacterial activity. The minimum inhibitory concentration (MIC) of the methanol extract ranged between 1.56 and 12.5 mg/ml. The results of this study provide support for the use of A. procumbens L. in Iran for traditional medicines.

Key concepts: Petroleum ether, Antibacterial activity, Chloroform, Pathogenic bacteria, Methanol, Ethanol, Agar diffusion test, Chemistry

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