1972•Psychological ReportsRequires access

Some Effects of Scopolamine on Acquisition and Extinction Performance in Rats

Donald F. McCoy

Abstract

2 experiments indicated that .4- and .6mg/kg doses of scopolamine blocked the normal course of response decrement in extinction. In Exp. I, this extinction-suppression effect was observed over repeated extinction sessions, despite an intervening session without the drug. Exp. II also indicated that scopolamine inhibited learning and disrupted performance of a learned task. The relationship of these results to Carlton's (1963) cholinergic inhibition hypothesis is indicated.

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Key concepts: Extinction (optical mineralogy), Scopolamine, Psychology, Cholinergic, Session (web analytics), Developmental psychology, Task (project management), Neuroscience