1976•European Journal of ImmunologyRequires access

Concentrations of three hapten‐binding immunoglobulins in pooled normal human serum

K. Karjalaninen, O. Mäkelä

Abstract

The amount of natural anti-DNP-cap, anti-NIP-cap or anti-ABA-TYR in human IgM was measured by using immunoabsorbents and hapten elution. We found that 1.0% of pooled human IgM is specific for DNP-cap, 0.2% for NIP-cap and 0.02% for ABA-TYR. Haptens NIP and DNP were found to be cross-reactive when tested with natural antibodies even though they were not cross-reactive when tested with immune antibodies.

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Available abstract

Key concepts: NIP, Hapten, Antibody, Biology, Immune system, Molecular biology, Immunology, Materials science