2005Antimicrobial Agents and ChemotherapyOpen access

High Rate of Resistance to Quinupristin-Dalfopristin in Enterococcus faecium Clinical Isolates from Korea

Won Sup Oh, Kwan Soo Ko, Jae‐Hoon Song, Mi Young Lee, Sulhee Park, Kyong Ran Peck, Nam Yong Lee, Choon Kwan Kim, Hyuck Lee, Shin‐Woo Kim, Hyun‐Ha Chang, Kim Ys, Sook‐In Jung, Jun Seong Son, Joon‐Sup Yeom, Hyun Kyun Ki, Gun-Jo Woo

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Abstract

We tested the in vitro susceptibilities of 603 enterococcal isolates from eight tertiary-care hospitals in Korea. The quinupristin-dalfopristin resistance rate in Enterococcus faecium was very high (25 isolates, 10.0%). It was suggested that both clonal spread and the sporadic emergence of quinupristin-dalfopristin-resistant isolates may explain the high prevalence of quinupristin-dalfopristin resistance in Korea.

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What this paper is about

We tested the in vitro susceptibilities of 603 enterococcal isolates from eight tertiary-care hospitals in Korea. The quinupristin-dalfopristin resistance rate in Enterococcus faecium was very high (25 isolates, 10.0%). It was suggested that both clonal spread and the sporadic emergence of quinupristin-dalfopristin-resistant isolates may explain the high prevalence of quinupristin-dalfopristin resistance in Korea.

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Available abstract

We tested the in vitro susceptibilities of 603 enterococcal isolates from eight tertiary-care hospitals in Korea. The quinupristin-dalfopristin resistance rate in Enterococcus faecium was very high (25 isolates, 10.0%). It was suggested that both clonal spread and the sporadic emergence of quinupristin-dalfopristin-resistant isolates may explain the high prevalence of quinupristin-dalfopristin resistance in Korea.

Key concepts: Dalfopristin, Quinupristin, Enterococcus faecium, Virginiamycin, Enterococcus, Biology, Microbiology, Antibiotics

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