Disorders of Consciousness

Abstract Disorders of consciousness are a spectrum of neurological disorders, encompassing coma, the vegetative state, and the minimally conscious state, in which patients acquire or develop an impairment of the two cardinal elements of consciousness–wakefulness and awareness. One of the main sources of complexity in this context is how to recognize and tell apart patients who retain some level of awareness from patients who do not. Indeed, in the absence of any direct means of assessing one's level of awareness, we are forced to indirectly infer a patient's state on the basis of their ability to perform behaviors that, appearing clearly voluntary, imply the presence of consciousness. In this contribution, we explore recent evidence showing how brain imaging can be harnessed to address the problem of consciousness in patients surviving severe brain injury. First, we focus on recent experiments demonstrating how neuroimaging can be used to detect the presence of voluntary “brain behavior” in otherwise non responsive patients, and to allow a rudimentary form of non muscle‐dependent communication strategy based solely on voluntary brain activity. Second, we discuss recent findings concerning network activity at different levels of awareness, and the relationship between thalamo cortical circuits and consciousness.