1986•Antimicrobial Agents and ChemotherapyOpen access

Bactericidal activity of ciprofloxacin against amikacin- and cefotaxime-resistant gram-negative bacilli and methicillin-resistant staphylococci

M S Simberkoff, J J Rahal

Abstract

The MICs and MBCs of ciprofloxacin were determined for clinical isolates of antibiotic-resistant aerobic bacteria. Decreased susceptibility to ciprofloxacin of cefotaxime- and amikacin-resistant Serratia marcescens and amikacin-resistant Pseudomonas aeruginosa strains were noted. The data suggest that ciprofloxacin susceptibility should be carefully monitored in treating patients with hospital-acquired bacterial infections.

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Available abstract

Key concepts: Amikacin, Cefotaxime, Ciprofloxacin, Microbiology, Serratia marcescens, Pseudomonas aeruginosa, Antibiotics, Bacilli