2007•Bioorganic & Medicinal Chemistry LettersOpen access

Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists

William A. Carroll, Douglas M. Kalvin, Arturo Perez Medrano, Alan S. Florjancic, Ying Wang, Diana L. Donnelly‐Roberts, Marian T. Namovic, George K. Grayson, Prisca Honoré, Michael F. Jarvis

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Key concepts: Chemistry, Tetrazole, Isostere, Triazole, 1,2,4-Triazole, Lead compound, Stereochemistry, Potency

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