2011•Bioorganic & Medicinal Chemistry LettersOpen access

Triazole-linked reduced amide isosteres: An approach for the fragment-based drug discovery of anti-Alzheimer’s BACE1 inhibitors

Christopher J. Monceaux, Chiho Hirata‐Fukae, Polo C.‐H. Lam, Maxim M. Totrov, Yasuji Matsuoka, Paul R. Carlier

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Key concepts: Isostere, Chemistry, Stereochemistry, Amide, Moiety, Docking (animal), Triazole, Amine gas treating

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