1967•The Journal of Cell BiologyOpen access

THE EFFECT OF THYMIDINE ON THE DURATION OF G1 IN CHINESE HAMSTER CELLS

Robert A. Tobey, E. Clay Anderson, Donald F. Petersen

Abstract

The generation time of a Chinese hamster cell line was varied by the use of different lots of sera in the culture media. Analysis of the division waves following thymidine synchronization showed that lengthening of the generation time was a result of an increase in duration of the G(1) phase and that thymidine treatment reduced the duration of G(1) back to its minimum value.

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Key concepts: Chinese hamster, Thymidine, Biology, Duration (music), Hamster, Cell division, Molecular biology, Cell culture