2010•Bioorganic & Medicinal Chemistry LettersOpen access

New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck

Nina Gommermann, Peter Buehlmayer, Anette von Matt, Werner Breitenstein, Keiichi Masuya, Bernard Pirard, Pascal Furet, Sandra W. Cowan‐Jacob, Gisbert Weckbecker

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Key concepts: Chemistry, Orally active, In vivo, Potency, Structure–activity relationship, Kinase, Enzyme, Selectivity

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New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck — Research Paper | ScholarLens