2010•Bioorganic & Medicinal Chemistry LettersRequires access

Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead, II

Yongchun Shen, Hong Du, Makoto Kotake, Tomohiro Matsushima, Masaki Goto, Hiroshi Shirota, Fabian Gusovsky, Xiangyi Li, Yimin Jiang, Shawn Schiller, Mark R. Spyvee, Heather Davis, Zhiyi Zhang, Robert D. Pelletier, Megumi Ikemori‐Kawada, Yoshiyuki Kawakami, Atsushi Inoue, Yuan Wang

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Key concepts: In vivo, Potency, Chemistry, In vitro, Natural product, Pharmacology, Lead compound, Lactone