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1982•Australian and New Zealand Journal of Obstetrics and GynaecologyRequires access

Vulvovaginal Candidiasis: Treatment and Recurrence

Graeme Dennerstein, Russell Langley

Open publisher page 4 citations

Abstract

This study compares the effectiveness of 6 treatment regimens for vulvovaginal candidiasis with 6 months' follow-up. 292 patients randomly allocated to the treatments completed the trial. Significant differences were found in the rates of recurrence within the different treatment groups. The most successful treatment was miconazole vaginal cream with oral nystatin, with a cure rate of 81%. The high rate of recurrence of this condition is noted and the need for at least 6 months' follow-up in future trials of candidacides is emphasized.

About this research paper

What this paper is about

This study compares the effectiveness of 6 treatment regimens for vulvovaginal candidiasis with 6 months' follow-up. 292 patients randomly allocated to the treatments completed the trial. Significant differences were found in the rates of recurrence within the different treatment groups. The most successful treatment was miconazole vaginal cream with oral nystatin, with a cure rate of 81%. The high rate of recurrence of this condition is noted and the need for at least 6 months' follow-up in future trials of candidacides is emphasized.

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OpenAlex reports 4 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

This study compares the effectiveness of 6 treatment regimens for vulvovaginal candidiasis with 6 months' follow-up. 292 patients randomly allocated to the treatments completed the trial. Significant differences were found in the rates of recurrence within the different treatment groups. The most successful treatment was miconazole vaginal cream with oral nystatin, with a cure rate of 81%. The high rate of recurrence of this condition is noted and the need for at least 6 months' follow-up in future trials of candidacides is emphasized.

Key concepts: Vulvovaginal Candidiasis, Miconazole, Medicine, Nystatin, Cure rate, Clinical trial, Internal medicine, Surgery

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