1995•Antimicrobial Agents and ChemotherapyOpen access

Comparison of effects of suture and cyanoacrylate tissue adhesive on bacterial counts in contaminated lacerations

John M. Howell, K A Bresnahan, Thomas O. Stair, Harinder Dhindsa, Becky Edwards

Abstract

We studied the effects of closing lacerations with suture or cyanoacrylate tissue adhesive on staphylococcal counts in inoculated guinea pig lacerations. Wounds closed with adhesive alone had lower counts than wounds containing suture material (P < 0.05). The results of a time-kill study were consistent with a bacteriostatic adhesive effect of the adhesive against Staphylococcus aureus.

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Key concepts: Cyanoacrylate, Fibrous joint, Adhesive, Staphylococcus aureus, Surgery, Micrococcaceae, Medicine, Guinea pig