2006BoneRequires access

A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys

Sanjay Kumar, Lauren Dare, Janice A. Vasko-Moser, Ian E. James, Simon Blake, David J. Rickard, Shing Mei Hwang, Thaddeus A. Tomaszek, Dennis S. Yamashita, Robert W. Marquis, Hye-Ja Oh, Jae-Uk Jeong, Daniel F. Veber, Maxine Gowen, Michael W. Lark, George B. Stroup

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Key concepts: Cathepsin K, Bone resorption, Osteoclast, Cathepsin, Resorption, Endocrinology, In vivo, Internal medicine

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A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys — Research Paper | ScholarLens