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Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo

Kenneth M. Kozloff, Luisa Quinti, Somying Patntirapong, Peter V. Hauschka, Ching‐Hsuan Tung, Ralph Weissleder, Umar Mahmood

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Key concepts: Cathepsin K, Osteoclast, Bone resorption, Downregulation and upregulation, In vivo, Cathepsin, Chemistry, Osteolysis

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Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo — Research Paper | ScholarLens