1991•Journal of Medical VirologyRequires access

Restriction site mapping of four genome types of adenovirus types 3 and 7 isolated in South America

Christian Niel, Márcia Terezinha Baroni de Moraes, Alicia S. Mistchenko, J.P.G. Leite, Selma A. Gomes

Abstract

New genome types of Ad3 and Ad7 were found among adenovirus (Ad) strains isolated from stools of children during epidemiological surveys made in São Paulo, Brazil, and Buenos Aires, Argentina. These were characterized by DNA analysis with 11 restriction endonucleases and showed a number of new restriction patterns, notably for BamHI, BcII, BgIII, HindIII, KpnI, and SmaI. Restriction maps of the genome types, named Ad3e1, Ad3e2, Ad3h, and Ad7h, were constructed and compared with those of Ad3p and Ad7p.

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Key concepts: HindIII, BamHI, Restriction enzyme, Genome, Restriction map, Biology, Genetics, Restriction site