1989•International Journal of Crude Drug ResearchRequires access

Effects ofEcballium elatriumJuice on Serum Bilirubin Concentration in Male Rats

Hamzeh H. Elayan, Munir N. Gharaibeh, Suheil Zmeili, Abdulazim S. Salhab

Open publisher page 12 citations

Abstract

The effect of Ecballium elatrium juice on serum bilirubin concentration was examined in male rats. Jaundice was induced surgically by ligating the main bile duct. Intravenous administration of 0.05 ml of the juice two days after ligation resulted in a significant decrease in bilirubin concentration 24 h following the injection, while 0.1 ml produced a more pronounced decrease in bilirubin concentration 2.4, and 24 h after the injection. Intranasal administration of 0.1 ml of the juice also produced a significant decrease in bilirubin concentration and two doses produced more marked decrease.

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What this paper is about

The effect of Ecballium elatrium juice on serum bilirubin concentration was examined in male rats. Jaundice was induced surgically by ligating the main bile duct. Intravenous administration of 0.05 ml of the juice two days after ligation resulted in a significant decrease in bilirubin concentration 24 h following the injection, while 0.1 ml produced a more pronounced decrease in bilirubin concentration 2.4, and 24 h after the injection. Intranasal administration of 0.1 ml of the juice also produced a significant decrease in bilirubin concentration and two doses produced more marked decrease.

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OpenAlex reports 12 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The effect of Ecballium elatrium juice on serum bilirubin concentration was examined in male rats. Jaundice was induced surgically by ligating the main bile duct. Intravenous administration of 0.05 ml of the juice two days after ligation resulted in a significant decrease in bilirubin concentration 24 h following the injection, while 0.1 ml produced a more pronounced decrease in bilirubin concentration 2.4, and 24 h after the injection. Intranasal administration of 0.1 ml of the juice also produced a significant decrease in bilirubin concentration and two doses produced more marked decrease.

Key concepts: Bilirubin, Jaundice, Serum bilirubin, Oral administration, Chemistry, Medicine, Internal medicine, Pharmacology

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