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2009•Journal of Bacteriology and VirologyOpen access

Antimicrobial Activity of Methanol Extract from Ficus carica Leaves Against Oral Bacteria

Miran Jeong, Hyeyoung Kim, Jeong‐Dan Cha

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Abstract

Ficus carica L. (fig) belongs to the mulberry tree (Moraceae) which is one of the oldest fruits in the world.It has been used as a digestion promoter and a cure for ulcerative inflammation and eruption in Korea.The present study investigated the antimicrobial activity of methanol (MeOH) extract of figs against oral bacteria.The MeOH extract (MICs, 0.156 to 5 mg/ml; MBCs, 0.313 to 5 mg/ml) showed a strong antibacterial activity against oral bacteria.The combination effects of MeOH extract with ampicillin or gentamicin were synergistic against oral bacteria.We suggest that figs could be employed as a natural antibacterial agent in oral care products.

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Ficus carica L. (fig) belongs to the mulberry tree (Moraceae) which is one of the oldest fruits in the world.It has been used as a digestion promoter and a cure for ulcerative inflammation and eruption in Korea.The present study investigated the antimicrobial activity of methanol (MeOH) extract of figs against oral bacteria.The MeOH extract (MICs, 0.156 to 5 mg/ml; MBCs, 0.313 to 5 mg/ml) showed a strong antibacterial activity against oral bacteria.The combination effects of MeOH extract with ampicillin or gentamicin were synergistic against oral bacteria.We suggest that figs could be employed as a natural antibacterial agent in oral care products.

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Available abstract

Ficus carica L. (fig) belongs to the mulberry tree (Moraceae) which is one of the oldest fruits in the world.It has been used as a digestion promoter and a cure for ulcerative inflammation and eruption in Korea.The present study investigated the antimicrobial activity of methanol (MeOH) extract of figs against oral bacteria.The MeOH extract (MICs, 0.156 to 5 mg/ml; MBCs, 0.313 to 5 mg/ml) showed a strong antibacterial activity against oral bacteria.The combination effects of MeOH extract with ampicillin or gentamicin were synergistic against oral bacteria.We suggest that figs could be employed as a natural antibacterial agent in oral care products.

Key concepts: Carica, Ficus, Moraceae, Antimicrobial, Traditional medicine, Bacteria, Antibacterial activity, Ampicillin

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