Reversal of cytogenetic action of 5-fluordeoxyuridine in barley root meristems by thymidine
M. Ondřej
Abstract
M. Ondřej
Abstract
The reversal of the cytogenetic effects of 5-fluordeoxyuridine, which are the gradual decrease of the mitotic index and the induction of chromosomal fragments was followed after addition of different concentrations of thymidine. Thymidine in the concentration 104 M reversed both the effects of FUdR completely. The concentration of thymidine 105 M partly reversed both the decrease of the mitotic index and the induction of chromosomal fragments. Uridine also caused some decrease of the cytogenetic effects of 5-fluordeoxyuridine.
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The reversal of the cytogenetic effects of 5-fluordeoxyuridine, which are the gradual decrease of the mitotic index and the induction of chromosomal fragments was followed after addition of different concentrations of thymidine. Thymidine in the concentration 104 M reversed both the effects of FUdR completely. The concentration of thymidine 105 M partly reversed both the decrease of the mitotic index and the induction of chromosomal fragments. Uridine also caused some decrease of the cytogenetic effects of 5-fluordeoxyuridine.
Key concepts: Thymidine, Mitotic index, Uridine, Mitosis, Root tip, Biology, Meristem, Molecular biology