2006•PubMedOpen access

Cutaneous finding in anti thymocyte globulin induced serum sickness.

Seyed Hesamedin Nabavizadeh, Mehran Karimi, Reza Amin

Abstract

Polyclonal anti-thymocyte globulin (ATG) is used as an immunosuppressive agent in the treatment of aplastic anemia (AA). Serum sickness is a recognized side effect of ATG. We observed abnormal skin manifestation in patient with aplastic anemia who had been treated with ATG. We conclude that abnormal immune function caused by aplastic anemia and ATG and corticosteroids may aggravate the signs of serum sickness.

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Available abstract

Key concepts: Aplastic anemia, Anti-thymocyte globulin, Globulin, Serum sickness, Immunology, Medicine, Anemia, Thymocyte